BSc, MSc, PhD (Molecular Parasitology)
Scientist D
(Former Ramalingaswami Fellow; Recognized as Exceptionally Meritorious Scientist, 2024)
ICMR- Regional Medical Research Centre, NE, Dibrugarh
I am a Scientist at ICMR-RMRCNE, working on the development of rapid, low-cost, and point-of-care molecular diagnostic platforms for both infectious and non-infectious diseases. My research focuses on CRISPR-Cas-based pathogen detection, antimicrobial resistance (AMR), tuberculosis, and malaria, with a special emphasis on microfluidic chip technologies and devices for use in resource-limited settings.
I have filed multiple patents on diagnostic assays and devices and have led projects on multiplexed molecular pathogen detection, including the development of point-of-care diagnostic devices and chip-based assays. I successfully transferred technology for a CRISPR-Cas-based TB detection system—the first-ever technology transfer in the history of ICMR-RMRCNE—marking a milestone in translating laboratory innovation into public health application and contributing to the vision of Atmanirbhar Bharat.
In addition to hardware innovation, my team has developed customized diagnostic software (RGlow) using artificial intelligence techniques, enabling offline, standalone analysis of fluorescence-based detection data. By leveraging AI during development, we enhanced the robustness, accuracy, and usability of diagnostic software tailored for low-resource settings.
Alongside my research, I am actively training and mentoring PhD students, equipping the next generation of scientists with a multidisciplinary approach and skills in molecular diagnostics, microfluidics, and translational research. Through this blend of innovation, capacity building, and alignment with the national vision of Viksit Bharat @2047, we aim to advance affordable diagnostic solutions that integrate cutting-edge molecular research, indigenous technology development, and public health impact.
Biotechnology, Molecular Diagnostics, Point of Care Diagnostics, CRISPR-Cas Technologies, Infectious diseases and malaria
Our lab specializes in utilizing advanced technologies to enhance diagnostic processes. We aim to transform disease detection and diagnosis by providing rapid, accurate, and cost-effective solutions. Our work is centered on improving early disease detection, enhancing patient outcomes, and contributing to global health efforts.
Our lab specializes in utilizing advanced technologies to enhance diagnostic processes. We are particularly focused on the development of point-of-care assays that provide rapid, accurate, and cost-effective solutions for disease detection. Our division is a leader in medical innovation, particularly in developing low-cost devices and applying CRISPR-Cas technology for diagnostic assay development. By leveraging the precision and versatility of the CRISPR-Cas system, we aim to revolutionize the detection and diagnosis of various diseases. Our goal is to improve early disease detection, enhance patient outcomes, and contribute to global health efforts through innovative diagnostic tools. Our work not only advances scientific knowledge but also has the potential to make a significant impact on public health by enabling more personalized and precise medical care.
ICMR-RMRCNE, Dibrugarh, and Meril Diagnostics Pvt Ltd have signed an MoA for the technology transfer of a CRISPR-Cas-based TB detection system developed by Dr Md Atique Ahmed & his team which has a turnaround time of ~3 hrs, this will add up to the efforts for TB elimination.
My background in molecular genetics has been enriched by extensive international experience. During my PhD and Postdoctoral research, I have worked on malaria-related molecular genetics projects across Malaysia, South Korea, and the United Kingdom. This global exposure has provided me with a comprehensive perspective on the challenges and innovations in the field. My expertise in molecular genetics and genomics informs my commitment to developing innovative diagnostic technologies.
List of Projects implemented:
1. Title: Development of rapid point of care diagnostics and drug resistance monitoring techniques for malaria in Northeast India using highly sensitive CRISPR based molecular tools.
2. Title: Microbial Detection within minutes: Development of rapid, low-cost, ultra-sensitive, mobile app based CRISPR Technologies for detection of clinically important bacterial infections and drug resistance.
3. Title: Field deployable CRISPR technologies for rapid, ultra-sensitive detection of malaria transmission biomarkers and sub-microscopic asymptomatic cases.
4. Title: Optimization and external validation of a CRISPR-Cas based tuberculosis detection system.
Group Working under Dr. Md Atique Ahmed
_logo.svg.png){kind=logo}
